Congenital heart disease, genetic syndromes, and major noncardiac malformations

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Genetic Syndromes associated with Congenital Heart Disease

Recent research has demonstrated that genetic alterations or variations contribute considerably to the development of congenital heart disease. Many kinds of genetic tests are commercially available, and more are currently under development. Congenital heart disease is frequently accompanied by genetic syndromes showing both cardiac and extra-cardiac anomalies. Congenital heart disease is the l...

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Congenital Heart Disease and Pregnancy

  ضایعات مادرزادی قلب خط مشی های گوناگونی از قبیل مراقبت دقیق بیماران باردار تا پیشگیری از بارداری و یا خاتمه آن را در زنان سن باروری ایجاب می کند. با پیشرفت روشهای درمان جراحی و دارویی در تصحیح و یا بر طرف کردن علایم بیماری مادرزادی، اکنون بسیاری از زنان مبتلا به مرحله باروری رسیده و باردار می شوند. اداره موفقیت آمیز این زنان در طی بارداری و بلافاصله بعد از زایمان به همکاری نزدیک بین متخصصین ...

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Noncardiac malformations in congenital heart disease: a retrospective analysis of 305 pediatric autopsies.

Congenital heart disease (CHD) is one of the important groups of birth defects and contributes significantly to infant mortality. Extracardiac anomalies occur in 15-45% of cases with CHD. In this retrospective study, autopsies of cases born alive and diagnosed as CHD between 1977-2002 at Hacettepe University Ihsan Doğramaci Children's Hospital, Pediatric Pathology Department, were investigated....

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Evaluating the overt extracardiac malformations in children with congenital heart disease in Khuzestan Province

Background: Extracardiac malformations can be seen in 20-45% of infants with congenital heart disease (CHD). Chromosomal abnormalities exist in 5-10% of patients with CHD. The aim of this study was to assess the frequency of overt extra cardiac malformations in children with CHD. Methods: This descriptive epidemiologic study was conducted on 720 patients with CHD referred to the pediatric ca...

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Congenital Malformations of the Heart

Two hundred and two operations on patients with a congenital ear malformation are presented. Special emphasis is placed on those patients seen in the past three years. The goal of surgery is normal, or near normal, hearing in the operated ear. The surgical approach is direct to the middle ear, and the mastoid air cell system is not opened. Temporalis fascia is used for the new tympanic membrane...

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ژورنال

عنوان ژورنال: European Journal of Pediatrics

سال: 2012

ISSN: 0340-6199,1432-1076

DOI: 10.1007/s00431-012-1838-x